I’ve noticed a frustrating pattern in medicine: we often fall in love with the snapshot. A single lab value, taken on a single day, becomes a proxy for an entire future—when biologically, the story is almost always a moving target. What makes the latest IgA nephropathy evidence so compelling is that it leans into the movement itself: the slope of eGFR over time. In my opinion, this is not just a technical improvement for kidney risk prediction. It’s a philosophical shift. Personally, I think the field has been too willing to treat “one number” as destiny, especially in slow-progressing diseases (Read more…)
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